References

¹ National Cancer Institute. NCI Dictionary of Cancer Terms. 2019. Available at: https://www.cancer.gov/publications/dictionaries/cancer-terms Accessed August 2019.

² LUNGevity. What You Need to Know about Biomarker Testing. Chicago: LUNGevity Foundation; 2017.

³ Genetics Home Reference. What is DNA? Available at: https://ghr.nlm.nih.gov/primer/basics/dna  Accessed August 2019.

⁴ Turski M. Driver and Passenger Mutations in Cancer Cell Genes. The Lundberg Institute. 2017; Available at http://lundberginstitute.043c1fe.netsolhost.com/driver-and-passenger-mutations-in-cancer-cell-genes/ Accessed August 2019.

⁵ National Cancer Institute. NCI Dictionary of Genetics Terms. Available at: https://www.cancer.gov/publications/dictionaries/genetics-dictionary  Accessed August 2019.

⁶ American Society for Cytotechnology. What is a Cell Block? Available at: http://qac.asct.com/workbench/cell-block-basics/204/01  Accessed August 2019.

⁷ Dana-Farber Cancer Institute. Cell-Free DNA. Available at: https://www.dana-farber.org/research/departments-centers-and-labs/integrative-research-centers/center-for-cancer-genome-discovery/cell-free-dna/ Accessed August 2019.

⁸ Kulangara K, et al. Clinical utility of the combined positive score for programmed death ligand-1 expression and the approval of Pembrolizumab for treatment of gastric cancer. Arch Path Lab Med. 2019;143(3):330-337. https://doi.org/10.5858/arpa.2018-0043-OA

⁹ FDA. Companion Diagnostics. 2018. Available at: https://www.fda.gov/medical-devices/vitro-diagnostics/companion-diagnostics Accessed August 2019.

¹⁰ Foundation Medicine. Genomic Testing FAQ. 2019. Available at: https://www.foundationmedicine.com/pages/common-physicians-questions  Accessed August 2019.

¹¹ Mendoza D, Garcia CA. Defining research reproducibility: What do you mean? Clin Chem. 2017;63(11): 1777. Available at: http://clinchem.aaccjnls.org/content/63/11/1777  Accessed August 2019.

¹² Croal B. The Communication of Critical and Unexpected Pathology Results. London: The Royal College of Pathologists; 2017. Available at: https://www.rcpath.org/uploads/assets/bb86b370-1545-4c5a-b5826a2c431934f5/The-communication-of-critical-and-unexpected-pathology-results.pdf  Accessed August 2019.

¹³ National Cancer Institute. Tumor Markers in Common Use. 2019. Available at:  https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-list  Accessed August 2019.

¹⁴ American Association for Clinical Chemistry. Lab Tests Online. 2019. Available at: https://labtestsonline.org/articles/patient-tools  Accessed August 2019.

¹⁵ NeoGenomics. BTK Inhibitor Acquired Resistance Panel. 2019. Available at: https://neogenomics.com/test-menu/btk-inhibitor-acquired-resistance-panel  Accessed August 2019.

¹⁶ National Cancer Institute. BRCA Mutations: Cancer Risk and Genetic Testing. 2019. Available at: https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet#q1  Accessed August 2019.

¹⁷ Naeim F, Rao PN, Son SX, Phan RT. Atlas of Hematology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches. 2nd ed. Elsevier, Inc.; 2018. https://doi.org/10.1016/C2015-0-05997-4.

¹⁸ Pernick N. CD25. Pathology Outlines. 2013. Available at: https://www.pathologyoutlines.com/topic/cdmarkerscd25.html  Accessed August 2019.

¹⁹ Jain N, O’Brien S. Chronic Lymphocytic Leukemia with Deletion 17p: Emerging Treatment Options. 2012. Available at: https://www.cancernetwork.com/hematologic-malignancies/chronic-lymphocytic-leukemia-deletion-17p-emerging-treatment-options Accessed August 2019.

²⁰ Helsten T, et al. The FGFR landscape in cancer: analysis of 4,853 tumors by next-generation sequencing. Clin Cancer Res. 2016;22(1):259-267. Available at: http://clincancerres.aacrjournals.org/content/22/1/259.full-text.pdf Accessed August 2019.

²¹ Genetics Home Reference. HRAS Gene. 2019. Available at: https://ghr.nlm.nih.gov/gene/HRAS# Accessed August 2019.

²² Roychowhurdy M. Stains: Ki67 / MIB1. Pathology Outlines. 2019. Available at: http://www.pathologyoutlines.com/topic/stainski67.html 

²³ Genetics Home Reference. MET Gene. Available at: https://ghr.nlm.nih.gov/gene/MET# Accessed August 2019.

²⁴ Mayo Clinic Laboratories. MGMT Promoter Methylation, Tumor. 2019. Available at: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/36733 Accessed August 2019.

²⁵ Association of Oncology Nurse Navigators+. Clinical Relevance and Rationale of Using MSI-H/dMMR Biomarkers in Immunotherapy of Colorectal Cancer and Other Solid Tumors. 2018. Available at: https://aonnonline.org/component/mams/?view=article&secid=180:faculty-perspectives-clinical-relevance-and-rationale-of-using-msi-h-dmmr-biomarkers-in-immunotherapy-of-colorectal-cancer-and-other-solid-tumors-part-3-of-a-4-part-series&artid=2068:clinical-relevance-and-rationale-of-using-msi-h-dmmr-biomarkers-in-immunotherapy-of-colorectal-cancer-and-other-solid-tumors   Accessed August 2019.

²⁶ Genetics Home Reference. MLH1 Gene. 2019. Available at: https://ghr.nlm.nih.gov/gene/MLH1#conditions Accessed August 2019.

²⁷ Genetics Home Reference. NRAS Gene. 2019. Available at: https://ghr.nlm.nih.gov/gene/NRAS# Accessed August 2019.

²⁸ Zhu J, et al. Is Neuron-specific enolase useful for diagnosing malignant pleural effusions? Evidence from a validated study and meta-analysis. BMC Cancer. 2017;17(590). https://doi.org/10.1186/s12885-017-3572-2

²⁹ NeoGenomics. NTRK NGS Fusion Profile. 2019. Available at: https://neogenomics.com/test-menu/ntrk-ngs-fusion-profile Accessed August 2019.

³⁰ NeoGenomics. p16. 2019. Available at: https://neogenomics.com/test-menu/p16   Accessed August 2019.

³¹ Genetics Home Reference. PIK3CA Gene. 2019. Available at: https://ghr.nlm.nih.gov/gene/PIK3CA#   Accessed August 2019.

³² Genetics Home Reference. PTEN Gene. Available at: https://ghr.nlm.nih.gov/gene/PTEN#conditions Accessed October 2019.

³³ Genetics Home Reference. RET Gene. 2019. Available at:  https://ghr.nlm.nih.gov/gene/RET#  Accessed August 2019.

³⁴ My Cancer Genome. EGFR T790M. 2019. Available at: https://www.mycancergenome.org/content/alteration/egfr-t790m  Accessed August 2019.

³⁵ Dean L. Irinotecan Therapy and UGT1A1 Genotype. Medical Genetics Summaries [Internet]. Bethesda: National Center for Biotechnology Information; 2015. Available at:  https://www.ncbi.nlm.nih.gov/books/NBK294473/ Accessed August 2019.

³⁶ The Kennedy Institute of Ethics. Bioethics Blogs: Acting on “Actionable Mutations.” 2015. Available at: https://bioethics.georgetown.edu/2015/09/acting-on-actionable-mutations  Accessed August 2019.